Article
Associations between genetic polymorphisms of membrane transporter genes and prognosis after chemotherapy: meta-analysis and finding from Seoul Breast Cancer Study (SEBCS).
The pharmacogenomics journal - 1 Sept 2018
Kim Ji-Eun, Choi Jaesung, Park JooYong, Park Chulbum, Lee Se Mi, Park Seong Eun, Song Nan, Chung Seokang, Sung Hyuna, Han Wonshik, Lee Jong Won, Park Sue K, Kim Mi Kyung, Noh Dong-Young, Yoo Keun-Young, Kang Daehee, Choi Ji-Yeob
Abstract excerpt
Membrane transporters can be major determinants of the pharmacokinetic profiles of anticancer drugs. The associations between genetic variations of ATP-binding cassette (ABC) and solute carrier (SLC) genes and cancer survival were investigated through a meta-analysis and an association study in the Seoul Breast Cancer Study (SEBCS). Including the SEBCS, the meta-analysis was conducted among 38 studies of genetic...
Topics
- Antineoplastic Agents
- Breast Neoplasms
- Female
- Humans
- Membrane Transport Proteins
- Polymorphism, Single Nucleotide
- Prognosis
- Progression-Free Survival
- Seoul