Article

Multi-level profiling of the Fmr1 KO rat unveils altered behavioral traits along with aberrant glutamatergic function

2023-07-24

Abstract excerpt

Fragile X Syndrome (FXS) is the most common cause of inherited intellectual disabilities and the most prevalent monogenic cause of autism. Although the knockout (KO) of the Fmr1 gene homolog in mice is primarily used for elucidating the neurobiological substrate of FXS, there is limited association of the experimental data with the pathophysiological condition in humans. The use of Fmr1 KO rats offers additional t...

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Literature Corpus work: 47e86a56-2fc3-51d5-92b0-23c03ebb078f
DOI: 10.21203/rs.3.rs-3099183/v1

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