Article

SDS-22 stabilizes the PP1 catalytic subunits GSP-1/-2 contributing to polarity establishment in <i>C. elegans</i> embryos

2025-01-08

Abstract excerpt

In many cells, cell polarity depends on the asymmetric distribution of the conserved PAR proteins, maintained by a balanced activity between kinases and phosphatases. The C. elegans one-cell embryo is polarized along the anterior-posterior axis, with the atypical protein kinase C PKC-3 enriched in the anterior, and the ring finger protein PAR-2 in the posterior. PAR-2 localization is regulated by PKC-3 and the PP...

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Literature Corpus work: 47e61cce-9fb1-5fd5-9642-6c39110c3708
DOI: 10.1101/2025.01.07.631699

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