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Article

Genetic drivers of progression in Alzheimers disease are distinct from disease risk

2025-11-19

Abstract excerpt

<h4>Background: </h4> Recent trials in Alzheimers disease (AD) demonstrate encouraging outcomes. These trials target risk mechanisms identified through genetic analysis whilst directly aiming to reduce progression rates. Evidence from other neurodegenerative diseases suggests the genetics of progression is distinct from risk of disease. To expand these initial successes and improve clinical outcomes further we nee...

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Literature Corpus work
47ae7194-5956-5550-854f-954635e4ce4f
DOI
10.1101/2025.11.17.25340247
Open publication

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Genetic drivers of progression in Alzheimers disease are distinct from disease riskDOI 10.1101/2025.11.17.25340247
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