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Article

Genetic determinants of disease progression in Alzheimer's disease.

Journal of Alzheimer's disease : JAD - 1 Jan 2015

Wang Xingbin, Lopez Oscar L, Sweet Robert A, Becker James T, DeKosky Steven T, Barmada Mahmud M, Demirci F Yesim, Kamboh M Ilyas

Abstract excerpt

There is a strong genetic basis for late-onset Alzheimer's disease (LOAD); thus far 22 genes/loci have been identified that affect the risk of LOAD. However, the relationships among the genetic variations at these loci and clinical progression of the disease have not been fully explored. In the present study, we examined the relationships of 22 known LOAD genes to the progression of AD in 680 AD patients...

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Source

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Identifiers

PMID: 25114068
DOI: 10.3233/JAD-140729
PMCID: PMC4245313

Genes

APOE
ADAM19
CASS4
EPHA1
FERMT2
PAX3
PIGQ
TREM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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