Article

Within-family heritability estimates for behavioural and disease phenotypes from 500,000 sibling pairs of diverse ancestries

2025-09-19

Abstract excerpt

<h4>ABSTRACT</h4> Quantification of the direct effect of genetic variation on human behavioural traits is important for understanding between-individual variation in socio-economic and health outcomes but estimates of their heritability can be biased by between-family indirect genetic effects. In contrast, using within-family variation in DNA sharing is robust to most confounding factors including shared environm...

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Literature Corpus work: 475ae0f5-9cf6-5367-96ec-169b51fd4855
DOI: 10.1101/2025.09.17.25336022

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