Article

Transcriptomics-Guided Drug Repurposing Identifies Candidate Compounds for Improving Long-Term Stroke Outcome

2026-03-10

Abstract excerpt

<h4>Background</h4> Functional recovery after ischemic stroke is a complex and polygenic process influenced by genetically regulated molecular pathways. Although genome-wide association studies (GWAS) have identified variants associated with stroke outcome, translating these findings into actionable therapeutic targets remains challenging. Transcriptome-wide association studies (TWAS) provide a framework to link...

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Literature Corpus work: 474d2c7c-aec8-5df9-9105-513f7783270e
DOI: 10.64898/2026.03.09.26347942

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