Article

Repurposing the atypical antidepressant trazodone for atherosclerotic cardiovascular disease

2021-06-29

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>. Current lipid-lowering drugs often leave significant residual risk for adverse outcomes. Identification of previously approved drugs for new indications, drug repurposing, may provide a cost effective alternative to <italic>de novo</italic> drug developing.<bold>Objectives</bold>. We combined clinical, transcriptomic, computational, and experimental strategies t...

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Literature Corpus work: 1a9186ac-baab-5e65-9e68-c8dd1875b60c
DOI: 10.21203/rs.3.rs-567817/v1

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