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Multi-omics analysis reveals aspirin is associated with reduced risk of Alzheimer’s disease

2025-04-08

Abstract excerpt

The urgent need for safe and effective therapies for Alzheimer’s disease (AD) has spurred a growing interest in repurposing existing drugs to treat or prevent AD. In this study, we combined multi-omics and clinical data to investigate possible repurposing opportunities for AD. We performed transcriptome-wide association studies (TWAS) to construct gene expression signatures of AD from publicly available GWAS summa...

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Literature Corpus work
f8c8df58-4b4d-55da-8302-bf363d2cbfac
DOI
10.1101/2025.04.07.25325038
Open publication

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Multi-omics analysis reveals aspirin is associated with reduced risk of Alzheimer’s diseaseDOI 10.1101/2025.04.07.25325038
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