Article

Quantitative <i>in vivo</i> analyses reveal a complex pharmacogenomic landscape in lung adenocarcinoma

2020-01-29

Abstract excerpt

<h4>Abstract:</h4> The lack of knowledge about the relationship between tumor genotypes and therapeutic responses remains one of the most important gaps in enabling the effective use of cancer therapies. Here, we couple a multiplexed and quantitative platform with robust statistical methods to enable pharmacogenomic mapping of lung cancer treatment responses in vivo . We uncover a surprisingly complex map of gen...

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Literature Corpus work: 4744a932-e956-5228-b403-965d76d00d17
DOI: 10.1101/2020.01.28.923912

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