Article

Characterisation of non-essential genes required for survival under conditions of DNA stress

2018-01-01

Abstract excerpt

Genomic instability is a hallmark of cancer. Cancer progression depends on the development and amplification of mutations that alter the cellular response to threats to the genome. This can lead to DNA replication stress and the potential loss of genetic integrity of the newly formed cells. The study of the sophisticated systems of DNA replication has been an attractive area for research in human and cancer, yet,...

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Literature Corpus work: 47270a8e-607b-5c15-b179-6aa44dbd3cba
DOI: 10.17635/lancaster/thesis/235

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