Article

Sentinel <i>p16</i> <sup> <i>INK4a</i> </sup> + cells in the basement membrane form a reparative niche in the lung

2020-06-10

Abstract excerpt

Senescent cells are recognized drivers of aging-related decline in organ function, but deciphering the biology of senescence in vivo has been hindered by the paucity of tools to track and isolate senescent cells in tissues 1–4 . Deleting senescent cells from transgenic murine models have demonstrated therapeutic benefits in numerous age-related diseases 5–11 , but the identity, behavior, and function of the sen...

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Literature Corpus work: 470fdf95-cade-54fd-be9c-1208b5a71f83
DOI: 10.1101/2020.06.10.142893

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