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Article

Cellular Senescence Exacerbates Features of Aging in the Eyes

20 Sept 2023

Abstract excerpt

Aging is a process often associated with various age-related diseases. Senescence is one of the hallmarks of aging, and senescent cells acquire a complex, often pro-inflammatory, secretory phenotype termed the senescence-associated secretory phenotype (SASP). Here we show that ocular surface cells from human cornea become senescent upon X-irradiation, characterized by increased SA-β-gal activity, decreased cell...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39239324
DOI: 10.59368/agingbio.20230014

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