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Article

Senescent cells exhibit features of developmental signaling centres

2025-10-31

Abstract excerpt

<h4>ABSTRACT</h4> Cellular senescence is a state that contributes to tissue patterning during development and tissue repair, but which becomes misregulated in ageing and disease. The senescence-associated secretory phenotype (SASP) mediates many of the context-dependent effects, yet its molecular composition and evolutionary origins remain incompletely understood. Here, we characterize the SASP signature of devel...

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Literature Corpus work
24081605-8168-552f-aee7-a90c3b0fb222
DOI
10.1101/2025.10.30.685565
Open publication

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Senescent cells exhibit features of developmental signaling centresDOI 10.1101/2025.10.30.685565
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