Article

Cold-induced expression of a truncated Adenylyl Cyclase 3 acts as rheostat to brown fat function

2022-08-01

Abstract excerpt

Promoting brown adipose tissue (BAT) activity has been recognized as innovative therapeutic approach to improve obesity and metabolic disease. Whilst the molecular circuitry underlying thermogenic activation of BAT is well understood, the processes underlying rheostatic regulation of BAT to maintain homeostasis and avoid excessive energy dissipation remain ill-defined. Increasing cyclic AMP (cAMP) biosynthesis is...

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Literature Corpus work: 46eba4d5-2d49-545f-a1ab-97a23b18fac6
DOI: 10.1101/2022.08.01.502156

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