Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dynamic transcriptome changes during adipose tissue energy expenditure reveal critical roles for long noncoding RNA regulators

1 Aug 2017

Abstract excerpt

Enhancing brown fat activity and promoting white fat browning are attractive therapeutic strategies for treating obesity and associated metabolic disorders.To provide a comprehensive picture of the gene regulatory network in these processes, we conducted a series of transcriptome studies by RNA sequencing (RNA-seq) and quantified the mRNA and long noncoding RNA (lncRNA) changes during white fat browning (chronic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipokines, Inflammation, and Metabolic Diseases
Share to Adipose Tissue and Metabolism
Share to Cancer-related molecular mechanisms research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28763438
DOI: 10.1371/journal.pbio.2002176

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dynamic transcriptome changes during adipose tissue energy expenditure reveal critical roles for long noncoding RNA regulatorsPMID 28763438Read ↗

Chronic cAMP activation induces adipocyte browning through discordant biphasic remodeling of transcriptome and chromatin accessibilitySemantic proximity Read ↗

Brown and white adipose tissues: intrinsic differences in gene expression and response to cold exposure in miceSemantic proximity Read ↗

The long noncoding RNA Blnc1 orchestrates homeostatic adipose tissue remodeling to preserve metabolic healthSemantic proximity Read ↗

Molecular and cellular regulation of thermogenic fatSemantic proximity Read ↗

HOXC10 suppresses browning of white adipose tissuesSemantic proximity Read ↗

Aging impairs cold-induced beige adipogenesis and adipocyte metabolic reprogrammingSemantic proximity Read ↗

A long-non-coding RNA, <i>LINC00473</i> , confers the human adipose tissue thermogenic phenotype through enhanced cAMP responsivenessSemantic proximity Read ↗

Integrated gene expression profiles reveal a transcriptomic network underlying the thermogenic response in adipose tissueSemantic proximity Read ↗

Perirenal adipose tissue contains a subpopulation of cold-inducible adipocytes derived from brown-to-white conversionSemantic proximity Read ↗

Adipocyte RNA-binding protein CELF1 promotes beiging of white fat through stabilizing Dio2 mRNASemantic proximity Read ↗

Aging impairs cold-induced beige adipogenesis and adipocyte metabolic reprogrammingSemantic proximity Read ↗

Aging impairs cold-induced beige adipogenesis and adipocyte metabolic reprogrammingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.