Article

REBASTINIB, OLVEREMBATINIB, AND NAS-181 INHIBIT <i>MYCOBACTERIUM ABSCESSUS</i> BY DISRUPTING MYCOTHIOL HOMEOSTASIS

2025-08-23

Abstract excerpt

<h4>ABSTRACT</h4> Nontuberculous mycobacteria (NTM), particularly Mycobacterium abscessus , pose a major clinical challenge due to intrinsic drug resistance and limited therapeutic options. In this study, we evaluated three repurposed kinase inhibitors, such as rebastinib, olverembatinib, and NAS-181for their antimycobacterial potential against M. abscessus . All three compounds displayed measurable in vitro ac...

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Literature Corpus work: 46b74213-8712-5484-9e29-02e4e5d86afa
DOI: 10.1101/2025.08.22.671851

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REBASTINIB, OLVEREMBATINIB, AND NAS-181 INHIBIT <i>MYCOBACTERIUM ABSCESSUS</i> BY DISRUPTING MYCOTHIOL HOMEOSTASISDOI 10.1101/2025.08.22.671851Read

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