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Mycothione reductase as a potential target in the fight against Mycobacterium abscessus infections

12 Dec 2023

Abstract excerpt

ABSTRACT While infections caused by Mycobacterium abscessus complex (MABC) are rising worldwide, the current treatment of these infections is far from ideal due to its numerous shortcomings thereby increasing the urge for novel drug targets. In this study, mycothione reductase (Mtr) was evaluated for its potential as a drug target for MABC infections since it is a key enzyme needed in the recycling of mycothiol,...

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PMID: 38085034
DOI: 10.1128/msphere.00669-23

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