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Article

Pathogen Box screening for hit identification against Mycobacterium abscessus

26 Apr 2018

Abstract excerpt

Mycobacterium abscessus is a rapidly growing life-threatening mycobacterium with multiple drug-resistance mechanisms. However, there is no official regimen for M. abscessus therapy. In this study, we screened the Pathogen Box, which contains 400 drug-like molecules active against neglected diseases, to identify active molecules targeting Mycobacterium abscessus using resazurin live/dead assays. In this screening...

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PMID: 29698397
DOI: 10.1371/journal.pone.0195595

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