Article

Epigenetic therapy remodels the immune synaptic cytoskeleton to potentiate cancer susceptibility to γδ T cells

2020-05-02

Abstract excerpt

<h4>ABSTRACT</h4> γδ T cells are a distinct subgroup of T cells that bridge the innate and adaptive immune systems and can attack cancer or virus-infected cells in an MHC-unrestricted manner. Despite its antitumor ability in both autologous and allogeneic settings, earlier trials of adoptive γδ T cell transfer in solid tumors had limited success due to limitations in cell expansion and the lack of a strategy to m...

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Literature Corpus work: 466da0c1-7bfa-561a-8372-2ccac9691041
DOI: 10.1101/2020.04.30.069955

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