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Article

Epigenetic modulation of immunotherapy and implications in head and neck cancer

5 Jan 2021

Abstract excerpt

Cancer progression is facilitated by distinct mechanisms developed by cancer cells to avoid immune recognition and clearance. The clinical application of immune checkpoint blockade (ICB), via monoclonal antibodies blocking PD-1/PD-L1 and CTLA4, has achieved promising durable therapeutic response in various cancer types, including recurrent and metastatic head and neck squamous cell carcinomas (HNSCC). HNSCC...

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PMID: 33403469
DOI: 10.1007/s10555-020-09944-0

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