Article

EZH2 Inhibition Boosts Tumor Immunogenicity and TIL Reactivity in Lung Cancer

2025-07-17

Abstract excerpt

Lung cancer, the leading cause of cancer-related death in the United States, remains a significant public health burden. One of the most personalized treatments to date uses a patient’s own tumor-infiltrating lymphocytes (TILs) as a cellular therapy to target the tumor. Endogenous TIL activity is also essential for immune checkpoint inhibitor (ICI) effectiveness. However, responses to immunotherapies vary due to i...

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Literature Corpus work: 90c31998-5d02-5971-967d-92d59e580e48
DOI: 10.1101/2025.07.12.663845

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