CellRank for directed single-cell fate mapping

Abstract excerpt

<title>Abstract</title> <p>Computational trajectory inference enables the reconstruction of cell-state dynamics from single-cell RNA sequencing experiments. However, trajectory inference requires that the direction of a biological process is known, largely limiting its application to differentiating systems in normal development. Here, we present CellRank (https://cellrank.org) for mapping the fate of single cell...

Topics

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• Cancer Cells and Metastasis
• CAR-T cell therapy research
• CRISPR and Genetic Engineering
• Neonatal Respiratory Health Research
• Single-cell and spatial transcriptomics

Identifiers and source

Literature Corpus work

7609ba77-c472-58b9-ab5a-f77ec8fa89a5

DOI

10.21203/rs.3.rs-94819/v1