Article

Characterization of cell-fate decision landscapes by estimating transcription factor dynamics

2022-04-01

Abstract excerpt

Modulation of gene expression during differentiation by transcription factors promotes cell diversity. Despite their role in cell fate decisions, no experimental assays estimate their regulatory activity in a high-throughput manner and at the single-cell resolution. We present FateCompass for identifying lineage-specific transcription factors across differentiation. It uses single-cell transcriptomics data to infe...

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Literature Corpus work: cd529332-6d1d-58d9-9f0f-bf3516db2cdb
DOI: 10.1101/2022.04.01.486696

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