Article
Efficient transdifferentiation of human dermal fibroblasts into skeletal muscle.
Journal of tissue engineering and regenerative medicine - 1 Feb 2018
Boularaoui Selwa Mokhtar, Abdel-Raouf Khaled M A, Alwahab Noaf Salah Ali, Kondash Megan E, Truskey George A, Teo Jeremy Choon Meng, Christoforou Nicolas
Abstract excerpt
Skeletal muscle holds significant regenerative potential but is incapable of restoring tissue loss caused by severe injury, congenital defects or tumour ablation. Consequently, skeletal muscle models are being developed to study human pathophysiology and regeneration. Their physiological accuracy, however, is hampered by the lack of an easily accessible human cell source that is readily expandable and capable of...
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