Article
Dystrophin deficiency impairs cell junction formation during embryonic myogenesis
2023-12-07
Abstract excerpt
<h4>Summary</h4> Mutations in the DMD gene lead to Duchenne muscular dystrophy, a severe X-linked neuromuscular disorder that manifests itself as young boys acquire motor functions. DMD is typically diagnosed at 2 to 4 years of age, but the absence of dystrophin negatively impacts muscle structure and function before overt symptoms appear in patients, which poses a serious challenge in the optimization of standa...
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Identifiers and source
- Literature Corpus work
- 759d5a7d-d253-57eb-b961-e50f77057a7a
- DOI
- 10.1101/2023.12.05.569919