Article

Human fallopian tube single-cell analysis reveals monocytic transcriptional and interaction changes in high-grade serous ovarian cancers

2023-07-16

Abstract excerpt

<h4>Summary</h4> Tumorigenesis for most high-grade serous ovarian cancers (HGSCs) likely initiates from fallopian tube (FT) epithelia. While epithelial subtypes have been characterized using single-cell RNA- sequencing (scRNA-Seq), heterogeneity of other cellular compartments and their involvement in tumor progression are poorly defined. Integrated analysis of human FT scRNA-Seq data and other relevant tissues, i...

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Literature Corpus work: 4632481b-add4-52fe-83eb-f81f4bb6a775
DOI: 10.1101/2023.07.14.549073

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