Article

Integrated analysis of single-cell and bulk transcriptomic data reveals altered cellular composition and predictive cell types in endometriosis

2024-11-20

Abstract excerpt

<title>Abstract</title> <p>The early diagnosis of endometriosis is delayed and the clinical treatment is difficult, which causes severe economic burden to the patients. A comprehensive study of the cell classification and composition of endometriosis, is essential for early diagnosis and pathogenesis. This study utilized single-cell data as a reference to accurately deconvolute cell types within bulk transcriptom...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f1cba5e1-b90e-5c3a-975d-87b510cfa8c1
DOI: 10.21203/rs.3.rs-5277508/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Integrated analysis of single-cell and bulk transcriptomic data reveals altered cellular composition and predictive cell types in endometriosisDOI 10.21203/rs.3.rs-5277508/v1Read

Single-cell transcriptomic analysis of endometriosis provides insights into fibroblast fates and immune cell heterogeneitySemantic proximity Read

Single‐cell transcriptomic atlas of different endometriosis indicating that an interaction between endometriosis‐associated mesothelial cells (EAMCs) and ectopic stromal cells may influence progesterone resistanceSemantic proximity Read

Single-Cell Profiling Reveals Altered Endometrial Cellular Features Across the Menstrual Cycle in Endometriosis PatientsSemantic proximity Read

Whole-tissue deconvolution and scRNAseq analysis identify altered endometrial cellular compositions and functionality associated with endometriosisSemantic proximity Read

Mapping single-cell transcriptomes of endometrium reveals potential biomarkers in cancerSemantic proximity Read

A comprehensive cell profiling reveals new cell subtypes and immune dysfunction in peritoneal fluid of endometriosisSemantic proximity Read

Single-cell transcriptomic analysis of endometriosisSemantic proximity Read

Single-cell analysis of endometrial proliferation and secretory phases in patients with endometriosis and normal populationSemantic proximity Read

An integrated single-cell reference atlas of the human endometriumSemantic proximity Read

Single-cell transcriptome analysis reveals endometrial immune microenvironment in minimal/mild endometriosisSemantic proximity Read

An integrated single-cell reference atlas of the human endometriumSemantic proximity Read

Single-Cell Transcriptomic Profiling and Machine Learning Integration Unveil Stromal Cell Heterogeneity in Endometriosis.Semantic proximity Read