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Identification of grade and origin specific cell populations in serous epithelial ovarian cancer by single cell RNA-seq

1 Nov 2018

Abstract excerpt

Here we investigated different cell populations within ovarian cancer using single-cell RNA seq: fourteen samples from nine patients with differing grades (high grade, low grade and benign) as well as different origin sites (primary and metastatic tumor site, ovarian in origin and fallopian in origin). We were able to identify sixteen distinct cell populations with specific cells correlated to high grade tumors,...

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PMID: 30383866
DOI: 10.1371/journal.pone.0206785

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