Article
Proto-MHC signatures in the lamprey genome
2025-03-17
Abstract excerpt
Jawless vertebrates, which diverged from jawed vertebrates approximately 550 million years ago, possess an adaptive immune system characterized by two distinct lineages of lymphocytes bearing unique antigen receptors. However, despite decades of research, the mechanism of antigen presentation in these organisms remains unclear. In this study, we report that chromosomes 22, 50, and 59 in the sea lamprey ( Petromyz...
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Identifiers and source
- Literature Corpus work
- 45e6c100-27af-523d-94dd-e0d24c295b61
- DOI
- 10.1101/2025.03.16.643586