Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Proto-MHC of Placozoans, a Region Specialized in Cellular Stress and Ubiquitination/Proteasome Pathways

12 Aug 2014

Abstract excerpt

The MHC is a large genetic region controlling Ag processing and recognition by T lymphocytes in vertebrates. Approximately 40% of its genes are implicated in innate or adaptive immunity. A putative proto-MHC exists in the chordate amphioxus and in the fruit fly, indicating that a core MHC region predated the emergence of the adaptive immune system in vertebrates. In this study, we identify a putative proto-MHC...

Source

Identifiers

PMID: 25114105
DOI: 10.4049/jimmunol.1401177

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Proto-MHC of Placozoans, a Region Specialized in Cellular Stress and Ubiquitination/Proteasome PathwaysPMID 25114105Read ↗

Proto-MHC signatures in the lamprey genomeSemantic proximity Read ↗

Subfunctionalization and constrained size of the immunoglobulin <i>loci</i> in <i>Ambystoma mexicanum</i>Semantic proximity Read ↗

Describing the diversity of Ag specific receptors in vertebrates: Contribution of repertoire deep sequencing.Semantic proximity Read ↗

Unique Features of Fish Immune Repertoires: Particularities of Adaptive Immunity Within the Largest Group of Vertebrates.Semantic proximity Read ↗

Ancient lineages of the keratin-associated protein (KRTAP) genes and their co-option in the evolution of the hair follicleSemantic proximity Read ↗

Ancient lineages of the keratin-associated protein (KRTAP) genes and their co- option in the evolution of the hair follicleSemantic proximity Read ↗

Single-cell transcriptome analysis of fish immune cells provides insight into the evolution of vertebrate immunitySemantic proximity Read ↗

Evolutionary History of the Toll-Like Receptor Gene Family across VertebratesSemantic proximity Read ↗

Chitinase family GH18: evolutionary insights from the genomic history of a diverse protein familySemantic proximity Read ↗

Evolution and developmental regulation of the major histocompatibility complex.Semantic proximity Read ↗

Antigen processing and presentation: evolution from a bird's eye view.Semantic proximity Read ↗

The chromosomal duplication model of the major histocompatibility complexSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.