Article

Single-cell transcriptome analysis of fish immune cells provides insight into the evolution of vertebrate immunity

2016-09-12

Abstract excerpt

The immune system of vertebrate species consists of many different cell types that have distinct functional roles and are subject to different evolutionary pressures. Here, we first analysed gene conservation of all major immune cell types in human and mouse. Our results revealed higher gene turnover and faster evolution of trans-membrane proteins in NK cells compared to other immune cell populations, and especial...

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Literature Corpus work: 2b061377-b8f8-57a3-92cf-fb545118c292
DOI: 10.1101/074344

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