Describing the diversity of Ag specific receptors in vertebrates: Contribution of repertoire deep sequencing.

doi:10.1016/j.dci.2017.02.018

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Describing the diversity of Ag specific receptors in vertebrates: Contribution of repertoire deep sequencing.

Developmental and comparative immunology - 1 Oct 2017

Castro Rosario, Navelsaker Sofie, Krasnov Aleksei, Du Pasquier Louis, Boudinot Pierre

Abstract excerpt

During the last decades, gene and cDNA cloning identified TCR and Ig genes across vertebrates; genome sequencing of TCR and Ig loci in many species revealed the different organizations selected during evolution under the pressure of generating diverse repertoires of Ag receptors. By detecting clonotypes over a wide range of frequency, deep sequencing of Ig and TCR transcripts provides a new way to compare the...

Topics

Adaptive Immunity
Animals
Genetic Variation
High-Throughput Nucleotide Sequencing
Receptors, Antigen, B-Cell
Receptors, Antigen, T-Cell
Vertebrates

Source

Open in PubMed

Identifiers

PMID: 28259700
DOI: 10.1016/j.dci.2017.02.018

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics