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Article

Genomic analysis of the immune gene repertoire of amphioxus reveals extraordinary innate complexity and diversity.

Genome research - 1 Jul 2008

Huang Shengfeng, Yuan Shaochun, Guo Lei, Yu Yanhong, Li Jun, Wu Tao, Liu Tong, Yang Manyi, Wu Kui, Liu Huiling, Ge Jin, Yu Yingcai, Huang Huiqing, Dong Meiling, Yu Cuiling, Chen Shangwu, Xu Anlong

Abstract excerpt

It has been speculated that before vertebrates evolved somatic diversity-based adaptive immunity, the germline-encoded diversity of innate immunity may have been more developed. Amphioxus occupies the basal position of the chordate phylum and hence is an important reference to the evolution of vertebrate immunity. Here we report the first comprehensive genomic survey of the immune gene repertoire of the amphioxus...

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Identifiers

PMID: 18562681
DOI: 10.1101/gr.069674.107
PMCID: PMC2493400

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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