Immunological Diversity Is a Cornerstone of Organismal Defense and Allorecognition across Metazoa.

doi:10.4049/jimmunol.2100754

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Article

Immunological Diversity Is a Cornerstone of Organismal Defense and Allorecognition across Metazoa.

Journal of immunology (Baltimore, Md. : 1950) - 15 Jan 2022

Buckley Katherine M, Dooley Helen

Abstract excerpt

The ongoing arms race between hosts and microbes has fueled the evolution of novel strategies for diversifying the molecules involved in immune responses. Characterization of immune systems from an ever-broadening phylogenetic range of organisms reveals that there are many mechanisms by which this diversity can be generated and maintained. Diversification strategies operate at the level of populations, genomes,...

Topics

Adaptive Immunity
Animals
Biological Evolution
Evolution, Molecular
Genetic Variation
Immunity, Cellular
Invertebrates
Receptors, Immunologic
Vertebrates

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Open in PubMed

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PMID: 35017209
DOI: 10.4049/jimmunol.2100754

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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