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Restoration of Susceptibility of <i>bla</i> <sub>NDM</sub> -bearing <i>Escherichia. coli</i> to Carbapenem Antibiotics by Exogenous <i>N</i> -acetylcysteine

2025-04-05

Abstract excerpt

The global spread of the New Delhi metallo-β-lactamase (NDM) -producing carbapenem-resistant Enterobacteriaceae pose a serious threat to public health, as NDM and its variants enzymes efficiently hydrolyze almost β-lactam antibiotics. The development of novel antibiotics or antibiotic adjuvants capable of eradicating antibiotic-resistance bacteria through multiple mechanisms represents a promising strategy for rev...

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Literature Corpus work
45b80566-f704-52b5-8d6b-0c21f4659695
DOI
10.1101/2025.03.31.646374
Open publication

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Restoration of Susceptibility of <i>bla</i> <sub>NDM</sub> -bearing <i>Escherichia. coli</i> to Carbapenem Antibiotics by Exogenous <i>N</i> -acetylcysteineDOI 10.1101/2025.03.31.646374
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