Article

Delaying cefiderocol resistance development in NDM-producing <i>Enterobacter cloacae</i> complex by combining cefiderocol with aztreonam <i>in vitro</i>

2024-02-13

Abstract excerpt

<h4>Background</h4> The rapid development of cefiderocol resistance poses a significant concern, particularly in Enterobacterales that produce New Delhi metallo-β-lactamase (NDM). This study explores the potential of inhibiting the development of cefiderocol resistance by combining cefiderocol with aztreonam. <h4>Methods</h4> A resistance induction experiment using 20 clinical isolates was performed to assess th...

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Literature Corpus work: 65e4ecac-652e-58b4-9b15-137af43775e1
DOI: 10.1101/2024.02.13.579981

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