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Copy number of the <i>bla</i> <sub>NDM-1</sub> gene (New Delhi metallo-β-lactamase-1) and meropenem susceptibility in Enterobacterales: Consideration for treatment with meropenem?

2025-09-03

Abstract excerpt

Some Enterobacterales carrying bla NDM were still susceptible to meropenem, exhibiting meropenem minimum inhibitory concentration (MIC) values below the clinical breakpoint. As this phenomenon is a rare observation, this study investigated the underlying regulatory mechanisms contributing to the low MIC values and evaluated the efficacy of meropenem as a therapeutic preference for such isolates. Six clinical bla...

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Literature Corpus work
6b4e9bb4-4a0f-50ff-8bf9-c0daff17b762
DOI
10.1101/2025.09.03.673909
Open publication

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Copy number of the <i>bla</i> <sub>NDM-1</sub> gene (New Delhi metallo-β-lactamase-1) and meropenem susceptibility in Enterobacterales: Consideration for treatment with meropenem?DOI 10.1101/2025.09.03.673909
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