Article

Transcriptome-based design of antisense inhibitors re-sensitizes CRE <i>E. coli</i> to carbapenems

2019-12-17

Abstract excerpt

Carbapenems are a powerful class of antibiotics, often used as a last-resort treatment to eradicate multidrug-resistant infections. In recent years, however, the incidence of carbapenem-resistant Enterobacteriaceae (CRE) has risen substantially, and the study of bacterial resistance mechanisms has become increasingly important for antibiotic development. Although much research has focused on genomic contributors...

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Literature Corpus work: 6491d2c0-7eaa-559f-863b-28483a86ea14
DOI: 10.1101/2019.12.16.878389

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