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Antibiotic-adjuvants abolish resistance conferred by the <i>Staphylococcus aureus</i> erythromycin resistance methyltransferase in an <i>Escherichia coli</i> model

2025-10-01

Abstract excerpt

<h4>ABSTRACT</h4> Enzyme-mediated resistance is among the main strategies bacteria use to evade antibiotic action. S -adenosylmethionine-dependent erythromycin resistance methyltransferases catalyze the methylation of 23S ribosomal RNA in bacteria, causing resistance to macrolides, lincosamides, and streptogramin type-B antibiotics. Given the diversity and number of identified variants of these enzymes, it is vi...

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Literature Corpus work
bdf2d319-d2a7-51fc-914b-562714d3b52e
DOI
10.1101/2025.10.01.679839
Open publication

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Antibiotic-adjuvants abolish resistance conferred by the <i>Staphylococcus aureus</i> erythromycin resistance methyltransferase in an <i>Escherichia coli</i> modelDOI 10.1101/2025.10.01.679839
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