Article

Investigating the function of the non-coding RNAs miR-27b and Herna1 in pathologic cardiac hypertrophy

2016-01-01

Abstract excerpt

Hypoxia inducible factor 1α (Hif1α) plays a key role in the induction and maintenance of heart disease and many direct Hif1α target genes have been identified. However, a number of genes show a Hif1α-dependent expression pattern although they lack the hypoxia response element (HRE) in their promoter for direct Hif1α binding. This work identified two modes of indirect gene regulation by Hif1α via a microRNA and enh...

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Literature Corpus work: 457f06a3-a8f7-5db1-be69-63a622ca2df0
DOI: 10.25560/67693

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