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Article

TXNIP regulates myocardial fatty acid oxidation via miR-33a signaling.

American journal of physiology. Heart and circulatory physiology - 1 Jul 2016

Chen Junqin, Young Martin E, Chatham John C, Crossman David K, Dell'Italia Louis J, Shalev Anath

Abstract excerpt

Myocardial fatty acid β-oxidation is critical for the maintenance of energy homeostasis and contractile function in the heart, but its regulation is still not fully understood. While thioredoxin-interacting protein (TXNIP) has recently been implicated in cardiac metabolism and mitochondrial function, its effects on β-oxidation have remained unexplored. Using a new cardiomyocyte-specific TXNIP knockout mouse and...

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Topics

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Share to AMP-Activated Protein Kinases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 27199118
DOI: 10.1152/ajpheart.00151.2016
PMCID: PMC4967210

Genes

TXNIP
CROT
HADHB
NFYA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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