Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Exploiting the hypoxia sensitive non-coding genome for organ-specific physiologic reprogramming.

Biochimica et biophysica acta - 1 Jul 2016

Bischof Corinne, Krishnan Jaya

Abstract excerpt

In this review we highlight the role of non-coding RNAs in the development and progression of cardiac pathology and explore the possibility of disease-associated RNAs serving as targets for cardiac-directed therapeutics. Contextually, we focus on the role of stress-induced hypoxia as a driver of disease development and progression through activation of hypoxia inducible factor 1α (HIF1α) and explore mechanisms...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiomyopathies
Share to Cell Hypoxia
Share to Cellular Microenvironment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cellular Reprogramming

Share to Genetic Therapy

Share to Hypoxia-Inducible Factor 1, alpha Subunit

Share to Myocardium

Share to RNA, Long Noncoding

Source

Identifiers

PMID: 26851074
DOI: 10.1016/j.bbamcr.2016.01.024

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Exploiting the hypoxia sensitive non-coding genome for organ-specific physiologic reprogramming.PMID 26851074Read ↗

Conditional HIF-1α Expression Produces a Reversible CardiomyopathySemantic proximity Read ↗

Long Noncoding RNAs in Pathological Cardiac Remodeling: A Review of the Update LiteratureSemantic proximity Read ↗

Theory and Applications of the (Cardio) Genomic Fabric Approach to Post-Ischemic and Hypoxia-Induced Heart FailureSemantic proximity Read ↗

Hypoxia-induced signaling in the cardiovascular system: pathogenesis and therapeutic targetsSemantic proximity Read ↗

Long Noncoding RNAs and Cardiac DiseaseSemantic proximity Read ↗

Beyond cardiomyocytes: Cellular diversity in the heart's response to exerciseSemantic proximity Read ↗

Single–cell transcriptional and epigenetic mapping reveals cellular and molecular mechanisms driving non-ischemic cardiac fibrosisSemantic proximity Read ↗

Long Non-Coding RNAs in Cardiac RemodelingSemantic proximity Read ↗

Long Non-coding RNAs: At the Heart of Cardiac Dysfunction?Semantic proximity Read ↗

Suppression of long noncoding RNA NEAT1 attenuates hypoxia-induced cardiomyocytes injury by targeting miR-378a-3pSemantic proximity Read ↗

Gestational stress induces the unfolded protein response, resulting in heart defects.Semantic proximity Read ↗

[Hypertrophic Cardiomyopathy as an Oligogenic Disease: Transcriptomic Arguments].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.