Article

MicroRNA-574 Regulates FAM210A Expression and Influences Pathological Cardiac Remodeling

2020-01-10

Abstract excerpt

Aberrant synthesis of mitochondrial proteins impairs cardiac function and causes heart disease. However, the mechanism of regulation of mitochondria encoded protein expression during cardiac disease remains underexplored. Here, we have shown that multiple pathogenic cardiac stressors induce the expression of miR-574 guide and passenger strands (miR-574-5p/3p) in both humans and mice. miR-574 knockout mice exhibit...

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Literature Corpus work: dc6a6337-aac3-5df1-bc7c-6fb9c9419e6d
DOI: 10.1101/2020.01.09.900712

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