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Article

The two-component regulator WalKR provides an essential link between cell wall homeostasis with DNA replication in <i>Staphylococcus aureus</i>

2023-02-28

Abstract excerpt

Among the 16 two-component systems (TCSs) in the opportunistic human pathogen Staphylococcus aureus , only WalKR is essential. Like orthologous systems in other Bacillota, S. aureus WalKR controls autolysins involved in peptidoglycan remodelling and is therefore intimately involved in cell division. However, despite the importance of WalKR in S. aureus , the basis for its essentiality is not understood and the...

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Identifiers and source

Literature Corpus work
45774d0e-7556-524e-88d1-8cf0c3fdbed0
DOI
10.1101/2023.02.27.530350
Open publication

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The two-component regulator WalKR provides an essential link between cell wall homeostasis with DNA replication in <i>Staphylococcus aureus</i>DOI 10.1101/2023.02.27.530350
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