Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Multi-strain Tn-Seq reveals common daptomycin resistance determinants in Staphylococcus aureus

18 Nov 2019

Abstract excerpt

Antibiotic-resistant Staphylococcus aureus remains a leading cause of antibiotic resistance-associated mortality in the United States. Given the reality of multi-drug resistant infections, it is imperative that we establish and maintain a pipeline of new compounds to replace or supplement our current antibiotics. A first step towards this goal is to prioritize targets by identifying the genes most consistently...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antimicrobial Resistance in Staphylococcus
Share to Bacteriophages and microbial interactions
Share to Genomics and Phylogenetic Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31738809
DOI: 10.1371/journal.ppat.1007862

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 17 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Multi-strain Tn-Seq reveals common daptomycin resistance determinants in Staphylococcus aureusPMID 31738809Read ↗

Comparative Tn-Seq reveals common daptomycin resistance determinants in <i>Staphylococcus aureus</i> despite strain-dependent differences in essentiality of shared cell envelope genesSemantic proximity Read ↗

Multidrug Intrinsic Resistance Factors in Staphylococcus aureus Identified by Profiling Fitness within High-Diversity Transposon LibrariesSemantic proximity Read ↗

The Secondary Resistome of Methicillin-Resistant Staphylococcus aureus to β-Lactam AntibioticsSemantic proximity Read ↗

Genome-Wide Identification of Antimicrobial Intrinsic Resistance Determinants in Staphylococcus aureusSemantic proximity Read ↗

Transposon library screening for identification of genetic loci participating in intrinsic susceptibility and acquired resistance to antistaphylococcal agents.Semantic proximity Read ↗

Strain-resolved CRISPRi-Seq reveals conserved antibiotic vulnerabilities in <i>Staphylococcus aureus</i>Semantic proximity Read ↗

Evolution of multidrug resistance during Staphylococcus aureus infection involves mutation of the essential two component regulator WalKR.Semantic proximity Read ↗

Staphylococcus aureus genetic loci impacting growth and survival in multiple infection environments.Semantic proximity Read ↗

<i>Staphylococcus aureus</i> TargetArray: Comprehensive Differential Essential Gene Expression as a Mechanistic Tool To Profile AntibacterialsSemantic proximity Read ↗

Systematic mapping of antibiotic cross-resistance and collateral sensitivity with chemical geneticsSemantic proximity Read ↗

The intrinsic macrolide resistome of Escherichia coliSemantic proximity Read ↗

Whole Genome Characterization of the Mechanisms of Daptomycin Resistance in Clinical and Laboratory Derived Isolates of Staphylococcus aureusSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.