Article
Transcriptional Analysis and Subcellular Protein Localization Reveal Specific Features of the Essential WalKR System in Staphylococcus aureus.
PloS one - 1 Jan 2016
Poupel Olivier, Moyat Mati, Groizeleau Julie, Antunes Luísa C S, Gribaldo Simonetta, Msadek Tarek, Dubrac Sarah
Abstract excerpt
The WalKR two-component system, controlling cell wall metabolism, is highly conserved among Bacilli and essential for cell viability. In Staphylococcus aureus, walR and walK are followed by three genes of unknown function: walH, walI and walJ. Sequence analysis and transcript mapping revealed a unique genetic structure for this locus in S. aureus: the last gene of the locus, walJ, is transcribed independently,...
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