Article

Regulation of neurogenesis and gliogenesis by the matricellular protein CCN2 in the mouse retina

2021-04-02

Abstract excerpt

Cellular communication network (CCN) 2 is an extracellular matrix protein with cell type- and context-dependent functions. Using a combination of mouse genetics and omic approaches, we show that CCN2 is expressed in early embryonic retinal progenitor cells (RPCs) and becomes restricted to fully differentiated Müller glial cells (MGCs) thereafter. Germline deletion of CCN2 in mice decreases BrdU labeling, reduces R...

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Literature Corpus work: 44d60941-95b6-5ebc-9144-d4afc812ec9b
DOI: 10.1101/2021.04.01.438112

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