Article

Modeling the Emergence of Phenotypic Heterogeneity in Vascularized Tumors

2021-01-01

Abstract excerpt

We present a mathematical study of the emergence of phenotypic heterogeneity in vascularized tumors. Our study is based on formal asymptotic analysis and numerical simulations of a system of nonlocal parabolic equations that describes the phenotypic evolution of tumor cells and their nonlinear dynamic interactions with the oxygen, which is released from the intratumoral vascular network. Numerical simulations are...

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Literature Corpus work: 44c121e9-3fd7-5947-92fd-24dcf09afae1
DOI: 10.1137/19m1293971

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