Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Mathematical Dissection of the Adaptation of Cell Populations to Fluctuating Oxygen Levels.

Bulletin of mathematical biology - 16 Jun 2020

Ardaševa Aleksandra, Gatenby Robert A, Anderson Alexander R A, Byrne Helen M, Maini Philip K, Lorenzi Tommaso

Abstract excerpt

The disordered network of blood vessels that arises from tumour angiogenesis results in variations in the delivery of oxygen into the tumour tissue. This brings about regions of chronic hypoxia (i.e. sustained low oxygen levels) and regions with alternating periods of low and relatively higher oxygen levels, and makes it necessary for cancer cells to adapt to fluctuating environmental conditions. We use a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Glycolysis
Share to Mathematical Concepts

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neovascularization, Pathologic

Share to Nonlinear Dynamics

Share to Oxidation-Reduction

Share to Oxygen

Share to Oxygen Consumption

Share to Stochastic Processes

Source

Identifiers

PMID: 32556703
DOI: 10.1007/s11538-020-00754-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Mathematical Dissection of the Adaptation of Cell Populations to Fluctuating Oxygen Levels.PMID 32556703Read ↗

A Mathematical Study of the Influence of Hypoxia and Acidity on the Evolutionary Dynamics of Cancer.Semantic proximity Read ↗

Spatio-temporal modelling of phenotypic heterogeneity in tumour tissues and its impact on radiotherapy treatment.Semantic proximity Read ↗

Eco-evolutionary causes and consequences of temporal changes in intratumoural blood flow.Semantic proximity Read ↗

Modelling cell adaptation using internal variables: Accounting for cell plasticity in continuum mathematical biology.Semantic proximity Read ↗

Modeling the Emergence of Phenotypic Heterogeneity in Vascularized TumorsSemantic proximity Read ↗

A Phenotype-Structured PDE Framework for Investigating the Role of Hypoxic Memory on Tumor Invasion under Cyclic Hypoxia.Semantic proximity Read ↗

Simulating Heterogeneous Tumor Cell PopulationsSemantic proximity Read ↗

A phenotype-structured model to reproduce the avascular growth of a tumor and its interaction with the surrounding environment.Semantic proximity Read ↗

Evolutionary dynamics of competing phenotype-structured populations in periodically fluctuating environments.Semantic proximity Read ↗

A hybrid cellular automaton model of clonal evolution in cancer: the emergence of the glycolytic phenotype.Semantic proximity Read ↗

Hypoxia increases the tempo of evolution in glioblastomaSemantic proximity Read ↗

Mathematical Models of Cancer Cell PlasticitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.